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Reporter mRNA-LNPs Synthesis
The RNA Medicine Core offers ready-to-use reporter mRNA-LNP products in 50 µg to 15 mg quantities, including EGFP-mRNA-LNP, mCherry-mRNA-LNP, EYFP-mRNA-LNP, RLuc-mRNA-LNP, NanoLuc-mRNA-LNP and firefly luciferase (FFLuc) mRNA-LNP, OVA mRNA-LNPs formulations, providing flexibility and scalability for your diverse research needs both in vitro and in vivo.
What We Offer
Catalog | Gene | Dry Run | In vitro Scale | In vivo Scale | Post purification & QC tests | Storage & Shelf Life | Timeline (Business days) |
|---|---|---|---|---|---|---|---|
siRNA LNP Kit | Custom gene | Client Spec (1 - 3 nmol) | / | / | No | freshly use | 1 |
mRNA LNP Kit | Custom gene | Client Spec (2 - 10 ug) | / | / | No | freshly use | 1 |
lncRNA-LNP | Custom gene | Client Spec (< 10 ug) | >= 100 ug | >500 ug | Yes | 4 °C, 3 months, sterile, open inside BSC | 3 |
circRNA-LNP | Custom gene | Client Spec (<10 ug) | >= 100 ug | >500 ug | Yes | -80 °C, 3 months, sterile, open inside BSC | 3 |
ASO-LNP | Custom gene | Client Spec (>=3 nmol) | >=10 nmol | >150 nmol | Yes | 4 °C, 3 months, sterile, open inside BSC | 3 |
siRNA-LNP | Custom gene | Client Spec (>=3 nmol) | >=10 nmol | >150 nmol | Yes | 4 °C, 3 months, sterile, open inside BSC | 3 |
mRNA-LNP | Custom gene | Client Spec (<10 ug) | >= 100 ug | >500 ug | Yes | -80 °C, 3 months, avoid multiple freeze thaw cycles | 3 |
mRNA-LNP | Reporter gene mRNA | / | >= 100 ug | >500 ug | Yes | -80 °C, 3 months, avoid multiple freeze thaw cycles | 1-3 |
Reporter mRNA-LNPs
RNA-LNPs Quality Control
QC | QC Method | Specification | Regular Test | Add-on |
|---|---|---|---|---|
Lipid composition | UPLC-ELSD | No | Yes | |
Endotoxin | Limulus Amebocyte Lysate assay | No | Yes | |
Encapsulate Efficiency | RiboGreen Assay | >90% | Yes | No |
Particle size | Dynamic Light Scattering | <120nm | Yes | No |
Particle Uniformity | Dynamic Light Scattering | <0.2 | Yes | No |
Concentration | RiboGreen Assay | Client Spec | Yes | No |
RNA-LNP Kits
We aim to offer cost-effective options to our customers at different stages of their research. In the early stages, we understand that researchers may have only small amounts of RNA samples for dry-run tests. We provide RNA-LNP Kits for transfecting cells in 24h-48h. The prepared mix is sufficient for six replicates in 96-well, 24-well, and 6-well transfections.
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